TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Allosteric inhibition of WNK1 (unknown origin) expressed in HEK293 cells co-expressing flag-OSR1 assessed as reduction in sorbitol-stimulated OSR1 ph...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 60nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 147nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 163nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2More data for this Ligand-Target Pair
Affinity DataKi: 342nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 357nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.1 uMMore data for this Ligand-Target Pair
Affinity DataKi: 549nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 596nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 4More data for this Ligand-Target Pair
Affinity DataKi: 607nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 611nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 626nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 735nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 808nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 853nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 3More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Nagoya City University
Curated by ChEMBL
Nagoya City University
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+3nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.27E+3nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+3nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 1.56E+3nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 1.75E+3nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.92E+3nMAssay Description:Displacement of [3H]-aldosterone from recombinant human mineralocorticoid receptor expressed in baculovirus infected insect cells incubated overnight...More data for this Ligand-Target Pair
Affinity DataKi: 1.96E+3nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor incubated overnight by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Compound is evaluated for the inhibition of porcine pancreatic (PP) elastaseMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database