TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Antagonist activity at adrenergic alpha1A receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Agonistic activity against Adenosine A2A receptor on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Antagonist activity at adrenergic alpha1B receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Agonistic activity against Adenosine A1 receptor on rat whole-brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Antagonist activity at adrenergic alpha1B receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Antagonist activity at adrenergic alpha1A receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Antagonist activity at adrenergic alpha1A receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair