Compile Data Set for Download or QSAR
maximum 50k data
Found 126 with Last Name = 'kouketsu' and Initial = 'a'
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  21nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  21nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19136(CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...)
Affinity DataIC50:  23nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19136(CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...)
Affinity DataIC50:  23nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)
Affinity DataIC50:  29nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)
Affinity DataIC50:  29nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)
Affinity DataIC50:  32nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  32nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)
Affinity DataIC50:  33nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  34nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  34nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  36nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  36nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50:  38nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  41nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  48nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)
Affinity DataIC50:  51nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50:  54nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50:  62nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19137(tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...)
Affinity DataIC50:  71nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475239(CHEMBL112234)
Affinity DataIC50:  72nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475246(CHEMBL320323)
Affinity DataIC50:  75nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50:  78nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475237(CHEMBL112105)
Affinity DataIC50:  79nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  81nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  81nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19138(tert-butyl N-[(1S)-1-(adamantan-1-ylcarbamoyl)-6-s...)
Affinity DataIC50:  82nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475250(CHEMBL113421)
Affinity DataIC50:  85nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19144((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475236(CHEMBL113159)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223653(CHEMBL332246)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223653(CHEMBL332246)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19147(cyclohexyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulf...)
Affinity DataIC50:  120nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19146(methyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50:  120nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50:  130nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50:  130nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19142((2S)-N-cyclopentyl-2-(2-hydroxyacetamido)-7-sulfan...)
Affinity DataIC50:  150nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)
Affinity DataIC50:  170nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19140((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...)
Affinity DataIC50:  190nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223648(CHEMBL322504)
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223648(CHEMBL322504)
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)
Affinity DataIC50:  220nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  280nMAssay Description:Inhibitory concentration against histone deacetylase of HeLa cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  280nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19140((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...)
Affinity DataIC50:  280nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19144((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...)
Affinity DataIC50:  310nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 126 total ) | Next | Last >>
Jump to: