Affinity DataKi: 0.126nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:PKi was measured by Histamine H3 receptor binding assay (N-alpha-MeHA) on rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+3nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+3nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.692nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrate assessed as remaining activity at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.851nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair