Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]methyl-spiperone from human dopamine D2s receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Namur
Curated by ChEMBL
University Of Namur
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Displacement of [3H]imipramine from human 5HT transporterMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I](+/-)-DOI from human 5HT2B receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Namur
Curated by ChEMBL
University Of Namur
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]BTCP from human DA transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Namur
Curated by ChEMBL
University Of Namur
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]nisoxetine from human NE transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]BRL43694 from human 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [125I]CYP from human 5HT1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H](-)-CGP12177 from human adrenergic beta1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]LSD from human 5HT5A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Competitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 490...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Inhibition of IDO by cell-free assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Uncompetitive inhibition of hexahistidyl-tagged human IDO1More data for this Ligand-Target Pair
Affinity DataKi: 3.24E+4nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Uncompetitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 4...More data for this Ligand-Target Pair
Affinity DataKi: 1.15E+7nMAssay Description:Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formy...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant IDO1 using L-Trp as substrate assessed as kynurenine level after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant IDO1 using L-Trp as substrate assessed as kynurenine level after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant IDO1 using L-Trp as substrate assessed as kynurenine level after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant IDO1 using L-Trp as substrate assessed as kynurenine level after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant IDO1 using L-Trp as substrate assessed as kynurenine level after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair