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Found 636 with Last Name = 'lassman' and Initial = 'm'
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364407(CHEMBL1950444)
Affinity DataIC50:  0.0390nMAssay Description:Inhibition of mouse recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364689(CHEMBL1951478)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364386(CHEMBL1950440)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364676(CHEMBL1951465 | US8785634, 1)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382913(CHEMBL2023210)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383421(CHEMBL2031595)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092190(CHEMBL3582482)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382899(CHEMBL2022787)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382904(CHEMBL2022793)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382913(CHEMBL2023210)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092142(CHEMBL3582477)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361786(CHEMBL1938522)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364685(CHEMBL1951474)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364407(CHEMBL1950444)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364679(CHEMBL1951468 | US8785634, 2)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364687(CHEMBL1951476 | US8785634, 8)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383421(CHEMBL2031595)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383427(CHEMBL2031588)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092182(CHEMBL3582470)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382905(CHEMBL2022794)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092185(CHEMBL3582474)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338033((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364676(CHEMBL1951465 | US8785634, 1)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364687(CHEMBL1951476 | US8785634, 8)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328246(3-(4-carbamoyl-1-(5-(1,1,1,3,3,3-hexafluoro-2-hydr...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092137(CHEMBL3582481)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382912(CHEMBL2023209 | US8569299, 4)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383425(CHEMBL2031590)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382910(CHEMBL2023207)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338029((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092191(CHEMBL3582483)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092183(CHEMBL3582471)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328247(4-(3-carboxyphenyl)-1-(5-(1,1,1,3,3,3-hexafluoro-2...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382898(CHEMBL2022786)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364669(CHEMBL1951458)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364685(CHEMBL1951474)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364387(CHEMBL1950439)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364689(CHEMBL1951478)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092186(CHEMBL3582475)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338007((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383420(CHEMBL2031596)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382912(CHEMBL2023209 | US8569299, 4)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383425(CHEMBL2031590)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383427(CHEMBL2031588)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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