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Found 90 with Last Name = 'low' and Initial = 'sc'
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314095(CHEMBL1090633)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314094(CHEMBL1090632)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314105(CHEMBL1090970 | N1,N4-bis((S)-1-((S)-1-((3R,8R,11S...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314093(CHEMBL1090631)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314102(CHEMBL1090640)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314090(CHEMBL1090278 | N-[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314103((R,S,S,3R,3'R,8R,8'R,11S,11'S,17S,17'S,20S,20'S,29...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314100((S)-N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314098(CHEMBL1090636)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314096(CHEMBL1090634)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314099(CHEMBL1090637 | N1,N5-bis((S)-1-((S)-1-((3R,8R,11S...)
Affinity DataIC50:  5nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314097(CHEMBL1090635 | N1,N1'-(ethane-1,2-diyl)bis(N4-((S...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314101((S)-N1,N5-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314091(CHEMBL1090279 | N-[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18...)
Affinity DataIC50:  18nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314104(CHEMBL1090969 | N1,N4-bis((S)-1-((S)-1-((3R,8R,11S...)
Affinity DataIC50:  20nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314092(CHEMBL1090280)
Affinity DataIC50:  50nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314078((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataIC50:  430nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030895(CHEMBL3356570)
Affinity DataIC50:  474nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030910(CHEMBL3356556)
Affinity DataIC50:  479nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataIC50:  520nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030896(CHEMBL3356569)
Affinity DataIC50:  562nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314088(CHEMBL1090276)
Affinity DataIC50:  580nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314084(CHEMBL1089952)
Affinity DataIC50:  600nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030894(CHEMBL3356559)
Affinity DataIC50:  637nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314087(CHEMBL1090275)
Affinity DataIC50:  710nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030901(CHEMBL3356564)
Affinity DataIC50:  807nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030908(CHEMBL3356558)
Affinity DataIC50:  860nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030920(CHEMBL3356547)
Affinity DataIC50:  904nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030902(CHEMBL3356563)
Affinity DataIC50:  968nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314086(CHEMBL1090274)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314079((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030906(CHEMBL3356560)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030903(CHEMBL3356562)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030900(CHEMBL3356565)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030932(CHEMBL3356132)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030931(CHEMBL3356133)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030926(CHEMBL3356541)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314085(CHEMBL1090273)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030919(CHEMBL3356548)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030915(CHEMBL3356552)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030917(CHEMBL3356550)
Affinity DataIC50:  2.89E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314089(CHEMBL1090277)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030905(CHEMBL3352858)
Affinity DataIC50:  3.17E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030924(CHEMBL3356543)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030913(CHEMBL3356554)
Affinity DataIC50:  4.53E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030911(CHEMBL3356555)
Affinity DataIC50:  4.96E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Institute

Curated by ChEMBL
LigandPNGBDBM50030916(CHEMBL3356551)
Affinity DataIC50:  7.86E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50451905(CHEMBL4217423)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SHP2 F285S mutant (1 to 525 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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