Affinity DataKi: 0.600nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15.8nMAssay Description:Binding affinity towards human mu-opioid receptors in CHO (Chinese hamster ovary) cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18.5nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 22.2nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 31.2nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51.6nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 98.6nMAssay Description:Binding affinity towards human mu-opioid receptors in CHO (Chinese hamster ovary) cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 107nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair