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Found 22 with Last Name = 'mularski' and Initial = 'cj'
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50284680((3S,4S)-3-Pyridin-3-ylmethyl-6-(quinolin-2-ylmetho...)
Affinity DataKi:  650nMAssay Description:Inhibition of [3H]-LTD4 binding to LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50284682(2-Benzyl-7-(quinolin-2-ylmethoxy)-1,2,3,4-tetrahyd...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of [3H]-LTD4 binding to LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50284681(2-Butyl-7-(quinolin-2-ylmethoxy)-1,2,3,4-tetrahydr...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of [3H]-LTD4 binding to LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of [3H]-LTD4 binding to LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50070921(3-[(3R,4R)-6-(5-Fluoro-benzothiazol-2-ylmethoxy)-4...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of [3H]-LTD4 binding to LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097898(CHEMBL355862 | N-(5-Cyclopropyl-1-quinolin-5-yl-1H...)
Affinity DataIC50:  59nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  140nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  150nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemic cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097896(CHEMBL354137 | N-(5-Cyclopropyl-1-naphthalen-1-yl-...)
Affinity DataIC50:  160nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097895(CHEMBL355071 | N-(5-Cyclopropyl-1-phenyl-1H-pyrazo...)
Affinity DataIC50:  350nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)
Affinity DataIC50:  560nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097897(CHEMBL352933 | N-(5-Methyl-1-phenyl-1H-pyrazole-4-...)
Affinity DataIC50:  830nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097899(CHEMBL167495 | N-(5-Methyl-1-quinolin-5-yl-1H-pyra...)
Affinity DataIC50:  860nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284680((3S,4S)-3-Pyridin-3-ylmethyl-6-(quinolin-2-ylmetho...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097897(CHEMBL352933 | N-(5-Methyl-1-phenyl-1H-pyrazole-4-...)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50070921(3-[(3R,4R)-6-(5-Fluoro-benzothiazol-2-ylmethoxy)-4...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  9.20E+3nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097898(CHEMBL355862 | N-(5-Cyclopropyl-1-quinolin-5-yl-1H...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097895(CHEMBL355071 | N-(5-Cyclopropyl-1-phenyl-1H-pyrazo...)
Affinity DataIC50:  1.28E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097896(CHEMBL354137 | N-(5-Cyclopropyl-1-naphthalen-1-yl-...)
Affinity DataIC50:  1.63E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)
Affinity DataIC50:  2.87E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097899(CHEMBL167495 | N-(5-Methyl-1-quinolin-5-yl-1H-pyra...)
Affinity DataIC50:  4.16E+5nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed