Affinity DataKi: 0.0110nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.163nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Binding affinity to human recombinant BChE in enzyme-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Binding affinity to human recombinant BChE in enzyme-substrate-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...More data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Competitive inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Competitive inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to human recombinant BChE in enzyme-inhibitor complexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Binding affinity to human recombinant BChE in enzyme-substrate-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Agonist activity at 5-HT4R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to human recombinant BChE in enzyme-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Binding affinity to human recombinant BChE in enzyme-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 169nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 252nMAssay Description:Binding affinity to human recombinant BChE in enzyme-substrate-inhibitor complexMore data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 790nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.25E+3nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.47E+4nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.21E+7nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0352nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair