Found 162 with Last Name = 'nevalainen' and Initial = 'tj' 
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.692nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrate assessed as remaining activity at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 0.851nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 17.4nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of GlyT1 (unknown origin) expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
