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Found 95 with Last Name = 'oehme' and Initial = 'f'
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118338(US8653111, 62)
Affinity DataIC50:  50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3527(US8524699, 18)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171824(US9085572, 34)
Affinity DataIC50:  180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118341(US8653111, 85)
Affinity DataIC50:  190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109268(US8609698, 10)
Affinity DataIC50:  260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118328(US8653111, 7)
Affinity DataIC50:  340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118344(US8653111, 103)
Affinity DataIC50:  350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118346(US8653111, 129)
Affinity DataIC50:  360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171821(US9085572, 6)
Affinity DataIC50:  430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3543(US8524699, 16)
Affinity DataIC50:  480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50:  490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118329(US8653111, 10)
Affinity DataIC50:  500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118331(US8653111, 17)
Affinity DataIC50:  560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118347(US8653111, 166)
Affinity DataIC50:  690nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171827(US9085572, 46)
Affinity DataIC50:  700nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3555(US8524699, 3)
Affinity DataIC50:  700nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118345(US8653111, 113)
Affinity DataIC50:  740nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118330(US8653111, 12)
Affinity DataIC50:  750nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171823(US9085572, 26)
Affinity DataIC50:  760nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118333(US8653111, 45)
Affinity DataIC50:  780nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171822(US9085572, 23)
Affinity DataIC50:  860nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3591(US8524699, 7)
Affinity DataIC50:  880nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3623(US8524699, 28)
Affinity DataIC50:  890nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109271(US8609698, 65)
Affinity DataIC50:  900nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109269(US8609698, 18)
Affinity DataIC50:  910nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3629(US8524699, 46)
Affinity DataIC50:  930nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324535(3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118337(US8653111, 61)
Affinity DataIC50:  1.10E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3643(US8524699, 44)
Affinity DataIC50:  1.12E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324529(3-({9-[Benzyl(methyl)]amino}nonanoyl(hydroxy)amino...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118336(US8653111, 60)
Affinity DataIC50:  1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118334(US8653111, 50)
Affinity DataIC50:  1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171826(US9085572, 43)
Affinity DataIC50:  1.50E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324534(3-{[8-(Dimethylamino)octanoyl](hydroxy)amino}propa...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324536(3-{[10-(Dimethylamino)decanoyl](hydroxy)amino}prop...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109272(US8609698, 80)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324530(CHEMBL1215590 | tert-Butyl 3-({Hydroxy[9-(methylam...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118343(US8653111, 101)
Affinity DataIC50:  1.70E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3644(US8524699, 55)
Affinity DataIC50:  1.70E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118332(US8653111, 43)
Affinity DataIC50:  1.80E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118340(US8653111, 83)
Affinity DataIC50:  1.90E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171829(US9085572, 48)
Affinity DataIC50:  1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171830(US9085572, 50)
Affinity DataIC50:  1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118335(US8653111, 55)
Affinity DataIC50:  2.00E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324529(3-({9-[Benzyl(methyl)]amino}nonanoyl(hydroxy)amino...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171828(US9085572, 47)
Affinity DataIC50:  2.20E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171825(US9085572, 35)
Affinity DataIC50:  2.30E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
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