TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Binding affinity to recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 1.07E+3nMAssay Description:Binding affinity to full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 1.25E+4nMAssay Description:Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of mouse anti-DNP IgE-stimulated beta-hexosaminidase release preincubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of anti-DNP IgE-stimulated TNFalpha release preincubated for 15 mins followed by mouse a...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated beta-hexosaminidase release preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated TNFalpha release preincubated for 15 mins followed by ionomycin ...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 4(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetProbable ubiquitin carboxyl-terminal hydrolase FAF-X(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human USP14More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 9.73E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetProtein kinase C beta type(Rattus norvegicus (rat))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of mouse anti-DNP IgE-stimulated beta-hexosaminidase release preincubated for 15 min...More data for this Ligand-Target Pair
TargetProtein kinase C beta type(Rattus norvegicus (rat))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of anti-DNP IgE-stimulated TNFalpha release preincubated for 15 mins followed by mou...More data for this Ligand-Target Pair
TargetProtein kinase C beta type(Rattus norvegicus (rat))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated TNFalpha release preincubated for 15 mins followed by ionomy...More data for this Ligand-Target Pair
TargetProtein kinase C beta type(Rattus norvegicus (rat))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated beta-hexosaminidase release preincubated for 15 mins followe...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human UCH-L1 using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetProtein kinase C beta type(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant full-length N-temrinal GST-tagged human PKC beta1 expressed in baculovirus infected Sf9 cells using TMB as substrate incuba...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair