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Found 2245 with Last Name = 'pae' and Initial = 'an'
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313283(1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  0.810nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50298360((R)-1-(7-ethyl-1H-furo[2,3-g]indazol-1-yl)propan-2...)
Affinity DataKi:  0.890nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50298361((R)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)
Affinity DataKi:  1nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50257963(2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine |...)
Affinity DataKi:  1nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50257011((S)-7-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-5-(...)
Affinity DataKi:  2nMAssay Description:Inhibition of IKKbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313283(1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50298362((R)-3-methyl-1-(4-(trifluoromethyl)-2,3-dihydroben...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112797(1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  2.60nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50159089(CHEMBL180523 | N,N-Dibutyl-2-[6,8-dichloro-2-(4-ch...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50045877(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50091831((R)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112787(1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol...)
Affinity DataKi:  3.90nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50179073((4R,9aR)-6-Cyclopropylmethoxymethyl-4-methyl-1,2,3...)
Affinity DataKi:  4nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112806(1-(2-Methoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazo...)
Affinity DataKi:  4.70nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50298359((8aR,12aS)-2-(2,6-difluorophenyl)-6,7,8a,9,10,11,1...)
Affinity DataKi:  5.20nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112792(1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  5.20nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112813(1-(2-Methoxy-phenyl)-4-{4-[3-(3-nitro-phenyl)-isox...)
Affinity DataKi:  6nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112785(1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  6.5nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50181821(CHEMBL202071 | O-(p-trifluoromethyl)benzyl-tyramin...)
Affinity DataKi:  6.90nMAssay Description:Competitive inhibition of recombinant human MAO-B using varying level of benzylamine substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112795(1-(2-Ethoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)-...)
Affinity DataKi:  9nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112808(1-(2-Methoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)...)
Affinity DataKi:  9.5nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112810(1-(2-Fluoro-phenyl)-4-[4-(3-styryl-isoxazol-5-yl)-...)
Affinity DataKi:  10nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112787(1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol...)
Affinity DataKi:  12nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112809(1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-...)
Affinity DataKi:  12nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112799(1-(2-Methoxy-phenyl)-4-[4-(3-styryl-isoxazol-5-yl)...)
Affinity DataKi:  15nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112786(1-Benzhydryl-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-...)
Affinity DataKi:  15nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112794(1-Phenyl-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-buty...)
Affinity DataKi:  15nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112804(1-Benzhydryl-4-{4-[3-(2,4-dimethoxy-phenyl)-isoxaz...)
Affinity DataKi:  16nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112807(1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  16nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  18nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human Dopamine receptor D2 long expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112812(1-Phenyl-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-pipe...)
Affinity DataKi:  18nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112790(1-(2-Ethoxy-phenyl)-4-{4-[3-(3-nitro-phenyl)-isoxa...)
Affinity DataKi:  19nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112788(1-Benzhydryl-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-y...)
Affinity DataKi:  19nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112805(1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  20nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112801(1-Benzhydryl-4-{4-[3-(3,4-dimethoxy-phenyl)-isoxaz...)
Affinity DataKi:  20nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313284((S)-2-((7-fluoro-2,3-dihydro-1H-inden-4-yloxy)meth...)
Affinity DataKi:  21nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112806(1-(2-Methoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazo...)
Affinity DataKi:  21nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112814(1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-...)
Affinity DataKi:  23nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112793(1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  24nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  25nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112802(1-Phenyl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-pipe...)
Affinity DataKi:  27nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112797(1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  28nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112800(1-Benzhydryl-4-{4-[3-(4-fluoro-phenyl)-isoxazol-5-...)
Affinity DataKi:  30nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112814(1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-...)
Affinity DataKi:  33nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112785(1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  34nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112795(1-(2-Ethoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)-...)
Affinity DataKi:  34nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112789(1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-buty...)
Affinity DataKi:  38nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112791(1-Benzhydryl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-...)
Affinity DataKi:  40nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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