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Found 188 with Last Name = 'pang' and Initial = 'yp'
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute of Science

LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  0.800nM ΔG°:  -51.4kJ/mole IC50:  2.40nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute of Science

LigandPNGBDBM10440((5S)-5-[(12-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  4.5nM ΔG°:  -47.2kJ/mole IC50:  16nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10440((5S)-5-[(12-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  19.6nM ΔG°:  -43.6kJ/mole IC50:  52nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataKi:  47.1nM ΔG°:  -41.4kJ/mole IC50:  114nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataKi:  175nM ΔG°:  -38.2kJ/mole IC50:  414nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataIC50:  0.770nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  1.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9047(Bis-THA inhibitor 5 | CHEMBL73800 | Hexylene-Linke...)
Affinity DataIC50:  3.80nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9047(Bis-THA inhibitor 5 | CHEMBL73800 | Hexylene-Linke...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8964(CHEMBL75274 | Homodimeric Tacrine Analog 3c | N-[8...)
Affinity DataIC50:  7.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8964(CHEMBL75274 | Homodimeric Tacrine Analog 3c | N-[8...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9441(CHEMBL1082738 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  8.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50080157((RS)-tacrine(10)-hupyridone | 5-[10-(1,2,3,4-Tetra...)
Affinity DataIC50:  8.80nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9440(CHEMBL1084775 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  10.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9435(CHEMBL1084369 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  12.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9436(CHEMBL1084096 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  13.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50080160(5-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyla...)
Affinity DataIC50:  26nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)
Affinity DataIC50:  28nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)
Affinity DataIC50:  28nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataIC50:  31nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataIC50:  31nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50080162(5-[9-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-nonyla...)
Affinity DataIC50:  36nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50366608(CHEMBL1202834)
Affinity DataIC50:  37nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9442(CHEMBL1082739 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  38.7nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50366606(CHEMBL1202835)
Affinity DataIC50:  43nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  44nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  44.5nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  45nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9433(CHEMBL1084367 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  45nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9431(CHEMBL1084094 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  47nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9430(CHEMBL1083791 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  52nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM50366605(CHEMBL1202836)
Affinity DataIC50:  53nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10446(2-methyl-N-{9-[(2-methylquinolin-4-yl)amino]nonyl}...)
Affinity DataIC50:  54.1nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9432(CHEMBL1084095 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  71nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM50080157((RS)-tacrine(10)-hupyridone | 5-[10-(1,2,3,4-Tetra...)
Affinity DataIC50:  82nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9437(CHEMBL1084530 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  83.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10452(Bivalent 4-Aminoquinoline 9f | N,N-di-4-Quinolyl-1...)
Affinity DataIC50:  87.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9426(CHEMBL258928 | Heterodimeric Tacrine-Based Inhibit...)
Affinity DataIC50:  89.4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  92nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  92nMAssay Description:Inhibition of rat serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  92nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  92nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10453(Bivalent 4-Aminoquinoline 9g | N-[8-(quinolin-4-yl...)
Affinity DataIC50:  94.3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10478(A2A.2HCl | Bis-THA inhibitor 1 | CHEMBL213377 | N-...)
Affinity DataIC50:  102nMAssay Description:Inhibition of rat serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10478(A2A.2HCl | Bis-THA inhibitor 1 | CHEMBL213377 | N-...)
Affinity DataIC50:  102nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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