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Found 1278 with Last Name = 'pham' and Initial = 'b'
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against human Caspase-3 using Ac-AspGluValAsp as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Mus musculus)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against Caspase-1 using Ac-TyrValAlaAsp-amc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344200((2R)-1-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344204((2R)-2-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344248(N-{6-[(3S)-4-acetyl-3-(methoxymethyl)piperazin-1-y...)
Affinity DataIC50:  1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344282(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  2.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344241(N-{6-[(2S)-2-(hydroxymethyl)-4-(morpholin-4-ylcarb...)
Affinity DataIC50:  2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119218(4-Benzyloxycarbonylamino-4-[1-(2-hydroxy-5-oxo-tet...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119218(4-Benzyloxycarbonylamino-4-[1-(2-hydroxy-5-oxo-tet...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344245(N-{6-[(2R)-4-acetyl-2-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50:  2.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344277(N-[6-(4-acetylpiperazin-1-yl)-2-methoxypyridin-3-y...)
Affinity DataIC50:  2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344224(N-{6-[4-(N′-cyano-N-methylcarbamimidoyl)pipe...)
Affinity DataIC50:  3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344222(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  3.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344205(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  3.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344239(N-{6-[(3S)-4-acetyl-3-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50:  3.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344290(N-[6-(1-acetylpiperidin-4-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  3.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119267(4-[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamo...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344279(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  3.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119245(4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hy...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119267(4-[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamo...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344240(N-{6-[(2S)-4-acetyl-2-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50:  3.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344217(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  3.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344264(N-[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]-6,6...)
Affinity DataIC50:  4.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344201(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344281(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344195(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344196(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344203(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  4.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344289(N-{6-(4-acetylpiperazin-1-yl)-2-[(1-oxidothietan-3...)
Affinity DataIC50:  4.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344285(N-[6-(4-acetylpiperazin-1-yl)-2-(oxetan-3-yloxy)py...)
Affinity DataIC50:  4.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235829(CHEMBL4098474)
Affinity DataIC50:  5nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235828(CHEMBL4090753)
Affinity DataIC50:  5nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344115(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  5.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344280(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  5.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344284(N-[6-(4-acetylpiperazin-1-yl)-2-(2,2,2-trifluoroet...)
Affinity DataIC50:  5.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344223(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344190(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344234(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  5.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344274(5,5-dimethyl-N-(2-methyl-2H-indazol-5-yl)-4-oxo-4,...)
Affinity DataIC50:  5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235831(CHEMBL4093260)
Affinity DataIC50:  6nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344210(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344244(N-{6-[(3R)-4-acetyl-3-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50:  6.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344263(N-[2-methoxy-4-(piperazin-1-yl)phenyl]-6,6-dimethy...)
Affinity DataIC50:  6.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119218(4-Benzyloxycarbonylamino-4-[1-(2-hydroxy-5-oxo-tet...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory concentration of compound required against Caspase-1 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119218(4-Benzyloxycarbonylamino-4-[1-(2-hydroxy-5-oxo-tet...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344291(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  6.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344202((2S)-1-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50:  6.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344225(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50:  6.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344213(N-[2-(2-hydroxy-2-methylpropoxy)-6-(morpholin-4-yl...)
Affinity DataIC50:  6.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 1278 total ) | Next | Last >>
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