Affinity DataKi: 0.00500nMAssay Description:Competitive reversible inhibition of human C-terminal His6-tagged CD73 expressed in HEK293 cells using AMP as substrate preincubated with substrate f...More data for this Ligand-Target Pair
Affinity DataKi: 0.00500nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in HEK293 cells using AMP as substrate preincubated for 1 h...More data for this Ligand-Target Pair
Affinity DataKi: 0.0141nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0152nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0447nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0504nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0575nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0940nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 0.102nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.108nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.118nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.128nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 0.149nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.151nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.179nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
Affinity DataKi: 0.204nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
Affinity DataKi: 0.243nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
Affinity DataKi: 0.269nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.279nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
Affinity DataKi: 0.312nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.341nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.483nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.517nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.541nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.568nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.575nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.576nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.615nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.637nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.671nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of PI3Kgamma (unknown origin) at 10 uM using PIP2 as substrate preincubated for 60 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair