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Found 210 with Last Name = 'pradeepan' and Initial = 'sg'
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5106(1,2,4-Oxadiazole Analogue 15c | 4-[(2S)-2-{[(1S)-2...)
Affinity DataIC50:  1.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5099(1,2,4-Oxadiazole Analogue 12c | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5105(1,2,4-Oxadiazole Analogue 15b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5103(1,2,4-Oxadiazole Analogue 13c | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5074(1,2,4-Oxadiazole Analogue 5m | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5075(1,2,4-Oxadiazole Analogue 5n | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5104(1,2,4-Oxadiazole Analogue 15a | 4-[(2S)-2-{[(1S)-2...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5102(1,2,4-Oxadiazole Analogue 13b | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5090(1,2,4-Oxadiazole Analogue 14e | 4-[(2S)-2-[1-(naph...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5086(1,2,4-Oxadiazole Analogue 14a | 4-[(2S)-2-(1-pheny...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5072(1,2,4-Oxadiazole Analogue 5k | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5085(1,2,4-Oxadiazole Analogue 12g | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5098(1,2,4-Oxadiazole Analogue 12b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  4.00E+3nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5100(1,2,4-Oxadiazole Analogue 12d | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5098(1,2,4-Oxadiazole Analogue 12b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5071(1,2,4-Oxadiazole Analogue 5j | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5101(1,2,4-Oxadiazole Analogue 13a | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5091(1,2,4-Oxadiazole Analogue 14f | 4-[(2S)-2-[1-(1H-i...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5096(1,2,4-Oxadiazole Analogue 5e | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5073(1,2,4-Oxadiazole Analogue 5l | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5087(1,2,4-Oxadiazole Analogue 14b | 4-[(2S)-2-[1-(thio...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5088(1,2,4-Oxadiazole Analogue 14c | 4-[(2S)-2-[1-(3,4-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5095(1,2,4-Oxadiazole Analogue 5d | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080177((S)-4-{(S)-2-[(S)-2-Acetylamino-3-(4-phosphonooxy-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5089(1,2,4-Oxadiazole Analogue 14d | 4-[(2S)-2-[1-(4-me...)
Affinity DataIC50:  6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5097(1,2,4-Oxadiazole Analogue 5f | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  6.00E+3nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080198((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  7.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50082328(CHEMBL102766 | N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,...)
Affinity DataIC50:  7.00E+3nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5097(1,2,4-Oxadiazole Analogue 5f | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5084(1,2,4-Oxadiazole Analogue 12f | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5095(1,2,4-Oxadiazole Analogue 5d | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5069(1,2,4-Oxadiazole Analogue 5i | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080193((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  8.00E+3nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5094(1,2,4-Oxadiazole Analogue 4j | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5082(1,2,4-Oxadiazole Analogue 12a | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  1.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080179(CHEMBL80765 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.20E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080186(CHEMBL77702 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  1.40E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5081(1,2,4-Oxadiazole Analogue 11 | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5093(1,2,4-Oxadiazole Analogue 4f | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5066(1,2,4-Oxadiazole Analogue 5b | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080180(CHEMBL311101 | Phosphoric acid mono-(4-{(S)-2-acet...)
Affinity DataIC50:  1.60E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080187((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  1.60E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5071(1,2,4-Oxadiazole Analogue 5j | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  1.80E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50082327(CHEMBL102765 | N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,...)
Affinity DataIC50:  1.80E+4nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50082331(CHEMBL320372 | Phosphoric acid mono-[4-(3-(2-methy...)
Affinity DataIC50:  1.90E+4nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080183((S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)...)
Affinity DataIC50:  2.10E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080181(CHEMBL77338 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  2.20E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50082330(3-(4-Phosphonooxy-benzyl)-N-{1-[3-(4-trifluorometh...)
Affinity DataIC50:  2.20E+4nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080196(CHEMBL78037 | Phosphoric acid mono-(4-{(S)-2-acety...)
Affinity DataIC50:  2.40E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080195(CHEMBL311740 | Phosphoric acid mono-(4-{(S)-2-acet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Binding affinity against Src-homology 2 (SRC SH2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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