Found 204 with Last Name = 'roggo' and Initial = 's' 
Affinity DataKi: 7.10nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity of the compound was tested against Murine caspase-1 (mCsp-1)More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 2.68E+3nMAssay Description:Binding affinity of the compound was tested against Murine caspase-1 (mCsp-1)More data for this Ligand-Target Pair
Affinity DataKi: 3.17E+3nMAssay Description:Binding affinity of the compound was tested against Murine caspase-1 (mCsp-1)More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 0.600nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity of the compound towards human Caspase-8More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-7 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-6 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-7 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity of the compound towards human Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: <10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: <10nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity of the compound towards human Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: 25nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 25nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Binding affinity of the compound towards mouse Caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration of compound required against Caspase-8 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Binding affinity of the compound towards mouse Caspase-1More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Binding affinity of the compound towards human Caspase-6More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 39nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 40nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: 56nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
