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Found 138 with Last Name = 'sergianni' and Initial = 'v'
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22038(2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexyl-2...)
Affinity DataKi:  0.370nM ΔG°:  -50.0kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224352(4-methoxy-N-(1-oxo-2-p-tolyl-1H-3,3,5,9b-tetraaza-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224355(CHEMBL235513 | N-(8-chloro-1-oxo-2-phenyl-1H-3,3a,...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224363(4-amino-8-chloro-2-p-tolyl-3,3a,5,9b-tetraaza-cycl...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224364(4-methoxy-N-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224350(4-amino-8-chloro-2-phenyl-3,3a,5,9b-tetraaza-cyclo...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224347(4-amino-2-(4-methoxy-phenyl)-3,3a,5,9b-tetraaza-cy...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224354(CHEMBL398787 | N-benzoyl-N-(1-oxo-2-phenyl-1H-3,3a...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKi:  9.30nM ΔG°:  -42.6kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22037(2-Phenylindolglyoxylamide Derivative, 6 | 2-[2-(4-...)
Affinity DataKi:  12nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224351(CHEMBL235717 | N-(8-chloro-1-oxo-2-p-tolyl-1H-3,3a...)
Affinity DataKi:  12.3nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50206936(CHEMBL375367 | N-isopropyl-2-(5-nitro-1H-indol-3-y...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224360(3-chloro-N-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-c...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50206941(CHEMBL376508 | N-(4-bromobenzyl)-2-(1H-indol-3-yl)...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22036(2-Phenylindolglyoxylamide Derivative, 5 | 7-nitrob...)
Affinity DataKi:  17nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224363(4-amino-8-chloro-2-p-tolyl-3,3a,5,9b-tetraaza-cycl...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224357(4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  20.1nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKi:  23nM ΔG°:  -40.5kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22035(2-Phenylindolglyoxylamide Derivative, 4 | 2-[2-(4-...)
Affinity DataKi:  23nM ΔG°:  -40.5kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224349(4-amino-2-p-tolyl-3,3a,5,9b-tetraaza-cyclopenta[a]...)
Affinity DataKi:  29.2nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50206939(CHEMBL223707 | N-(p-methylbenzyl)-5-nitroindol-3-y...)
Affinity DataKi:  31.3nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224356(4-amino-2-(4-chloro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  33.2nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224345(4-amino-2-phenyl-3,3a,5,9b-tetraaza-cyclopenta[a]n...)
Affinity DataKi:  34.6nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50165330(8-chloro-2-p-tolyl-5H-3,3a,5,9b-tetraaza-cyclopent...)
Affinity DataKi:  39.6nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224344(3-chloro-N-(1-oxo-2-p-tolyl-1H-3,3a,5,9b-tetraaza-...)
Affinity DataKi:  41.5nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50165335(2-(4-Chloro-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopen...)
Affinity DataKi:  41.9nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Universita Di Pisa

LigandPNGBDBM22034(2-Phenylindolglyoxylamide Derivative, 3 | 7-nitrob...)
Affinity DataKi:  42nM ΔG°:  -39.1kJ/molepH: 7.4 T: 2°CAssay Description:Assays were performed by incubating aliquots of rat kidney mitochondria suspensions with [3H]PK 11195 and a range of concentrations of the test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224362(1-benzyl-3-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-c...)
Affinity DataKi:  43.4nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224345(4-amino-2-phenyl-3,3a,5,9b-tetraaza-cyclopenta[a]n...)
Affinity DataKi:  43.9nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224349(4-amino-2-p-tolyl-3,3a,5,9b-tetraaza-cyclopenta[a]...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224365(1-(3-chloro-phenyl)-3-(1-oxo-2-phenyl-1H-3,3a,5,9b...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224359(1-(4-methoxy-phenyl)-3-(1-oxo-2-phenyl-1H-3,3a,5,9...)
Affinity DataKi:  49.1nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50165325(2-(4-Methoxy-phenyl)-5H-3,3a,5,9b-tetraaza-cyclope...)
Affinity DataKi:  49.8nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224349(4-amino-2-p-tolyl-3,3a,5,9b-tetraaza-cyclopenta[a]...)
Affinity DataKi:  50.6nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224347(4-amino-2-(4-methoxy-phenyl)-3,3a,5,9b-tetraaza-cy...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224348(CHEMBL235296 | N-[2-(4-chloro-phenyl)-1-oxo-1H-3,3...)
Affinity DataKi:  55.7nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50055261(CHEMBL75307 | N-Benzyl-2-(5-nitro-1H-indol-3-yl)-2...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224357(4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  65.2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224361(4-amino-8-chloro-2-(4-chloro-phenyl)-3,3a,5,9b-tet...)
Affinity DataKi:  67.5nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224350(4-amino-8-chloro-2-phenyl-3,3a,5,9b-tetraaza-cyclo...)
Affinity DataKi:  80.2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224352(4-methoxy-N-(1-oxo-2-p-tolyl-1H-3,3,5,9b-tetraaza-...)
Affinity DataKi:  80.9nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50206941(CHEMBL376508 | N-(4-bromobenzyl)-2-(1H-indol-3-yl)...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50165331(2-p-Tolyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]napht...)
Affinity DataKi:  86.5nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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