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Found 61 with Last Name = 'sridhar' and Initial = 's'
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataKi:  9.80E+3nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207386(CHEMBL3967165)
Affinity DataKi:  1.75E+4nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207381(CHEMBL3934940)
Affinity DataKi:  1.96E+4nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207370(CHEMBL3896540)
Affinity DataKi:  2.16E+4nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523558(CHEMBL4460401)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523568(CHEMBL4447493)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523562(CHEMBL4474072)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523560(CHEMBL4300203)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523569(CHEMBL4463796)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523561(CHEMBL4437104)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523567(CHEMBL4522729)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523566(CHEMBL4574382)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523565(CHEMBL4542773)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523564(CHEMBL4525849)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523563(CHEMBL4554438)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human UGT1A1 using bilirubin as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  990nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM50599144(CHEMBL5179012)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM50599144(CHEMBL5179012)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human UGT1A1 using bilirubin as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant rat UGT1A1 using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207386(CHEMBL3967165)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207381(CHEMBL3934940)
Affinity DataIC50:  8.72E+3nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre

Curated by ChEMBL
LigandPNGBDBM50599144(CHEMBL5179012)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207370(CHEMBL3896540)
Affinity DataIC50:  9.58E+3nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207390(CHEMBL3976270)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of recombinant rat UGT1A1 using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207395(CHEMBL3908464)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207371(CHEMBL3979181)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207379(CHEMBL3944368)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207388(CHEMBL3906649)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207373(CHEMBL3931385)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207394(CHEMBL3906497)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Homo sapiens (Human))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207385(CHEBI:6646 | Mahanimbine | Rel-(+)-Mahanimbine)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of pancreatic lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207376(CHEMBL3932922)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207393(CHEMBL3905980)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207378(CHEMBL3977704)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207387(CHEMBL3897958)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207396(CHEMBL3977167)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207382(CHEMBL3945483)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207380(CHEMBL3931968)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50207375(CHEMBL3982037)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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