Affinity DataKi: 0.000350nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.000570nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.000870nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.00150nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.00170nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.00200nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.00500nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.00900nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.00940nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Inhibition of human plasma kallikrein by Michaelis-menten analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0330nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.0340nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0360nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0490nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Inhibition of human thrombin using Tos-Gly-Pro-Arg-AMC as substrate after 600 secs by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0590nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
US Patent
The Medicines Company (Leipzig)
US Patent
Affinity DataKi: 0.0690nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of thrombin (unknown origin) using Tos-Gly-Pro-Arg-AMCA-TFA as a substrate incubated for 40 secs and measured every 15 secs interval for 2...More data for this Ligand-Target Pair
Affinity DataKi: 0.0750nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0770nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)
US Patent
The Medicines Company (Leipzig)
US Patent
Affinity DataKi: 0.0800nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.0830nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0830nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0840nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.0950nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate after 10 mins by UV/Vis photometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity to FXa (unknown origin) using Mes-DArg-Pro-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.102nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.108nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.114nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.119nMAssay Description:Inhibition of human thrombin using Tos-Gly-Pro-Arg-AMC as substrate after 600 secs by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition of thrombin (unknown origin) using Tos-Gly-Pro-Arg-AMCA-TFA as a substrate incubated for 40 secs and measured every 15 secs interval for 2...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Compound was measured for the inhibition of alpha-human thrombin by amidolytic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.259nMAssay Description:Inhibition of human thrombin using Tos-Gly-Pro-Arg-AMC as substrate after 600 secs by fluorimetric methodMore data for this Ligand-Target Pair