Affinity DataKi: 0.0700nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory activity against chicken gizzard smooth muscle calpainMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Tested for inhibitory activity against bovine cathepsin B.More data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Tested for inhibitory activity against calpainMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibitory activity against chicken gizzard smooth muscle calpainMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibitory activity against chicken gizzard smooth muscle calpainMore data for this Ligand-Target Pair
Affinity DataKi: 5.60E+4nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.891nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human CK1 epsilon using casein as substrate after 2 hrs in presence of [33P]-ATP by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK8/CyclinC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.29nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 2.29nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 2.57nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 2.57nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 2.69nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 2.88nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of HPGDS (unknown origin)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Sanofi-Aventis
Curated by ChEMBL
Sanofi-Aventis
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human DHODH by using blue indicator dye DCIPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.63nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 4.47nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Antagonistic activity against histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Antagonistic activity against histamine H1 receptorMore data for this Ligand-Target Pair