TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 5.70E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 5.90E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 7.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.56E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 4.89E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 7.68E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 9.83E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 1.45E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.76E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel
Curated by ChEMBL
Christian-Albrechts-University Kiel
Curated by ChEMBL
Affinity DataKi: 2.82E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat intact neuron FAAHMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of rat brain membrane FAAHMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GlyT2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of Orai1 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human GlyT2 expressed in FreeStyle 293-F suspension cells incubated for 30 mins before [3H]glycine addition and measured af...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Reversible inhibition of recombinant human GlyT2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake after 2 hrs by top count assa...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 152nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 214nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 259nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 259nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
University Of Sydney
Curated by ChEMBL
University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 313nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair