TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity towards human melanocortin receptor (hMC4R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSH; not determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 575nMAssay Description:Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSH; not determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 675nMAssay Description:Agonistic activity against human melanocortin receptor (hMC4R) for cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 675nMAssay Description:Agonist activity at human melanocortin receptor (hMC4R).More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity towards human melanocortin receptor hMC3R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Binding affinity towards human melanocortin receptor hMC1R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 5.82E+3nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity towards human Melanocortin 5 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMAssay Description:Binding affinity towards human melanocortin receptor hMC5R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Agonistic activity against human melanocortin receptor (hMC1R) for cAMP accumulationMore data for this Ligand-Target Pair