Compile Data Set for Download or QSAR
maximum 50k data
Found 260 with Last Name = 'yagaloff' and Initial = 'k'
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50184359((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50184359((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards human melanocortin receptor (hMC4R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451759(CHEMBL2371219)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174078(1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  13nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126087(CHEMBL415341 | MT-II cyclic peptide derivative)
Affinity DataIC50:  15nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124772((S)-2-{2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124773((S)-2-{(S)-3-(4-Bromo-phenyl)-2-[(S)-2-butyrylamin...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451761(CHEMBL2371218)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174073(4-(4-Ethoxy-phenyl)-1-pentanoylamino-cyclohexaneca...)
Affinity DataIC50:  43nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451762(CHEMBL2112920)
Affinity DataIC50:  50nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124775((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124766((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124772((S)-2-{2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-...)
Affinity DataIC50:  100nMAssay Description:Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121884(5-Bromo-2-pentanoylamino-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50:  105nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSH; not determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124775((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50:  150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121888(5-Dimethylamino-2-pentanoylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50:  150nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  150nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124770((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121884(5-Bromo-2-pentanoylamino-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50:  200nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451759(CHEMBL2371219)
Affinity DataIC50:  250nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124766((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124779((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  300nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124773((S)-2-{(S)-3-(4-Bromo-phenyl)-2-[(S)-2-butyrylamin...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451760(CHEMBL2371220)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124770((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  575nMAssay Description:Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  580nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  580nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSH; not determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124767((S)-2-{2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-...)
Affinity DataIC50:  600nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451762(CHEMBL2112920)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(CHEMBL384036 | MT-II cyclic peptide derivative)
Affinity DataIC50:  675nMAssay Description:Agonistic activity against human melanocortin receptor (hMC4R) for cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(CHEMBL384036 | MT-II cyclic peptide derivative)
Affinity DataIC50:  675nMAssay Description:Agonist activity at human melanocortin receptor (hMC4R).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124768((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124767((S)-2-{2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124768((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451760(CHEMBL2371220)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Binding affinity towards human melanocortin receptor hMC3R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174073(4-(4-Ethoxy-phenyl)-1-pentanoylamino-cyclohexaneca...)
Affinity DataIC50:  4.70E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121884(5-Bromo-2-pentanoylamino-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50:  4.90E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451761(CHEMBL2371218)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121884(5-Bromo-2-pentanoylamino-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50:  5.10E+3nMAssay Description:Binding affinity towards human melanocortin receptor hMC1R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126087(CHEMBL415341 | MT-II cyclic peptide derivative)
Affinity DataIC50:  5.82E+3nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174078(1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  7.10E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124779((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  9.60E+3nMAssay Description:Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Binding affinity towards human Melanocortin 5 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50:  1.33E+4nMAssay Description:Binding affinity towards human melanocortin receptor hMC5R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(CHEMBL384036 | MT-II cyclic peptide derivative)
Affinity DataIC50:  1.47E+4nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(CHEMBL384036 | MT-II cyclic peptide derivative)
Affinity DataIC50:  1.48E+4nMAssay Description:Agonistic activity against human melanocortin receptor (hMC1R) for cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 260 total ) | Next | Last >>
Jump to: