Affinity DataKi: 24nM ΔG°: -43.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -42.7kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 81nM ΔG°: -40.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 150nM ΔG°: -38.6kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 180nM ΔG°: -38.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 220nM ΔG°: -37.6kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 290nM ΔG°: -36.9kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Binding affinity to recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 1.07E+3nMAssay Description:Binding affinity to full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nM ΔG°: -33.5kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 1.27E+3nM ΔG°: -33.3kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.15E+3nM ΔG°: -30.4kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 4.41E+3nM ΔG°: -30.3kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+3nM ΔG°: -30.0kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataKi: 1.25E+4nMAssay Description:Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.34E+4nM ΔG°: -27.5kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 2.45E+4nM ΔG°: -26.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 5.40E+4nM ΔG°: -24.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
Affinity DataKi: 6.80E+4nM ΔG°: -23.5kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 4(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetProbable ubiquitin carboxyl-terminal hydrolase FAF-X(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Tokyo University Of Agriculture
Curated by ChEMBL
Tokyo University Of Agriculture
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human USP14More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Cavia porcellus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair