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Found 51 with Last Name = 'young' and Initial = 'hs'
TargetProcathepsin L(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM419133(BDBM429386 | GC376)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476968(SARS-CoV-2 3CLP and CoV inhibitor 15h)
Affinity DataIC50:  1nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476970(SARS-CoV-2 3CLP and CoV inhibitor 15j)
Affinity DataIC50:  4nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476967(SARS-CoV-2 3CLP and CoV inhibitor 15g)
Affinity DataIC50:  6.40nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM50594616(CHEMBL5170425)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476964(SARS-CoV-2 3CLP and CoV inhibitor 15d)
Affinity DataIC50:  13nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM50594612(CHEMBL5185160)
Affinity DataIC50:  13nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476973(SARS-CoV-2 3CLP and CoV inhibitor 15m)
Affinity DataIC50:  14nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM582824(US11524940, Compound 1149)
Affinity DataIC50:  14nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM50594614(CHEMBL5190756)
Affinity DataIC50:  14nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataIC50:  19nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476972(SARS-CoV-2 3CLP and CoV inhibitor 15l)
Affinity DataIC50:  19nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476963(SARS-CoV-2 3CLP and CoV inhibitor 15c)
Affinity DataIC50:  20nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476959(SARS-CoV-2 3CLP and CoV inhibitor 5)
Affinity DataIC50:  20nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476959(SARS-CoV-2 3CLP and CoV inhibitor 5)
Affinity DataIC50:  20nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476962(SARS-CoV-2 3CLP and CoV inhibitor 15b)
Affinity DataIC50:  22nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476974(SARS-CoV-2 3CLP and CoV inhibitor 15n)
Affinity DataIC50:  22nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM419133(BDBM429386 | GC376)
Affinity DataIC50:  23nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM50594615(CHEMBL5204224)
Affinity DataIC50:  24nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476971(SARS-CoV-2 3CLP and CoV inhibitor 15k)
Affinity DataIC50:  33nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM496896(US11312704, Compound 101 | US11351149, Example 49 ...)
Affinity DataIC50:  40nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM423462(US11753373, Compound A-5-a | WO2006061714, P38.2 |...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM50594613(CHEMBL5189649)
Affinity DataIC50:  49nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM476972(SARS-CoV-2 3CLP and CoV inhibitor 15l)
Affinity DataIC50:  52nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM423462(US11753373, Compound A-5-a | WO2006061714, P38.2 |...)
Affinity DataIC50:  60nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476966(SARS-CoV-2 3CLP and CoV inhibitor 15f)
Affinity DataIC50:  64nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476961(SARS-CoV-2 3CLP and CoV inhibitor 15a)
Affinity DataIC50:  64nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476975(SARS-CoV-2 3CLP and CoV inhibitor 15o)
Affinity DataIC50:  72nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476965(SARS-CoV-2 3CLP and CoV inhibitor 15e)
Affinity DataIC50:  86nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM476968(SARS-CoV-2 3CLP and CoV inhibitor 15h)
Affinity DataIC50:  116nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476969(SARS-CoV-2 3CLP and CoV inhibitor 15i)
Affinity DataIC50:  126nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM419133(BDBM429386 | GC376)
Affinity DataIC50:  190nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  190nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM476972(SARS-CoV-2 3CLP and CoV inhibitor 15l)
Affinity DataIC50:  201nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM423462(US11753373, Compound A-5-a | WO2006061714, P38.2 |...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM50594616(CHEMBL5170425)
Affinity DataIC50:  400nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM476965(SARS-CoV-2 3CLP and CoV inhibitor 15e)
Affinity DataIC50:  444nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM476968(SARS-CoV-2 3CLP and CoV inhibitor 15h)
Affinity DataIC50:  464nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM50594616(CHEMBL5170425)
Affinity DataIC50:  470nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM50594612(CHEMBL5185160)
Affinity DataIC50:  640nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM496896(US11312704, Compound 101 | US11351149, Example 49 ...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM419133(BDBM429386 | GC376)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM496896(US11312704, Compound 101 | US11351149, Example 49 ...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM476958(SARS-CoV-2 3CLP and CoV inhibitor 4)
Affinity DataIC50:  1.50E+3nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM423462(US11753373, Compound A-5-a | WO2006061714, P38.2 |...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Alberta Edmonton

Curated by ChEMBL
LigandPNGBDBM50594612(CHEMBL5185160)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM476965(SARS-CoV-2 3CLP and CoV inhibitor 15e)
Affinity DataIC50:  2.85E+3nMAssay Description:Pure SARS-CoV-2 3CLP was obtained as previously described in detail, and the enzymatic activity was confirmed according to an established protocol; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Alberta

LigandPNGBDBM50489171(CHEMBL2316337 | acs.jmedchem.1c00409_ST.364)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM50594616(CHEMBL5170425)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM496896(US11312704, Compound 101 | US11351149, Example 49 ...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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