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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Beta-1 adrenergic receptor
(Mus musculus)
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
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Affinity Data
Ki: 5.30nM
Assay Description:
Displacement of [3H]CGP12177 from mouse beta1 adrenoceptor expressed in HEK293T cell membranes
More data for this Ligand-Target Pair
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Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
UniversitÄT WÜRzburg
Curated by
PDSP K
i
Database
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
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Affinity Data
Ki: 22.4nM
More data for this Ligand-Target Pair
Target Info
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
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Affinity Data
Ki: 250nM
Assay Description:
Displacement of [3H]CGP12177 from human beta2 adrenoceptor expressed in CHO cell membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
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MCE
KEGG
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In Depth
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PubMed
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Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.15E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
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PC sid
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In Depth
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Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
UniversitÄT WÜRzburg
Curated by
PDSP K
i
Database
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
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Affinity Data
Ki: 9.07E+3nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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antibodypedia
GoogleScholar
Ligand Info
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ChEBI
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MCE
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PubMed
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Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
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KEGG
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antibodypedia
GoogleScholar
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Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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ChEBI
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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ChEBI
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MCE
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
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MCE
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
UniversitÄT WÜRzburg
Curated by
PDSP K
i
Database
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 15nM
pH: 7.4 T: 2°C
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
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MCE
KEGG
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PC sid
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In Depth
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Article
PubMed
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Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.30E+4nM
Assay Description:
Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 150nM
Assay Description:
Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 150nM
Assay Description:
Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 200nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by
ChEMBL
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.30E+4nM
Assay Description:
Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
UniversitÄT WÜRzburg
Curated by
PDSP K
i
Database
Ligand
BDBM25751
(Bisoprolol | Bisoprolol fumarate | Concor | [2-hyd...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.14E+3nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI