Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 47 hits in this display
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
Ki: 26nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
Ki: 26nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
Ki: 450nMAssay Description:Antagonist activity at human 5HT7 receptor expressed in HEK-CNG cells assessed as effect on cAMP production by fluorescence based assayMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 2.90nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 2.90nMAssay Description:Inhibition of SERT in rat brain synaptosomes assessed as reduction in [3H]-5-HT uptake measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 2.90nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 2.90nMAssay Description:Inhibition of [3H]serotonin reuptake in rat brain synaptosomes SERT after 15 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 12nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in xenopus oocytes assessed as inhibition of 5HT-induced effect by electrophysiological methodMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using resorufin benzyl ether after 30 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 3.90E+4nMAssay Description:Inhibition of human recombinant CYP2C9 using dibenzylfluorescein after 45 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
IC50: 4.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxy-3-cyanocoumarin after 28 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)