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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
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Affinity Data
Ki: 5.90nM
Assay Description:
Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...
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Target
Free fatty acid receptor 1
(Mus musculus)
TBA
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
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Affinity Data
EC50: 19nM
Assay Description:
Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretion
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
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Affinity Data
EC50: 18.6nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometry
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Target
Free fatty acid receptor 4
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
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Affinity Data
EC50: 6.31E+3nM
Assay Description:
Agonist activity at GPR120 assessed as stimulation of calcium mobilization
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
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Copy InChI
Affinity Data
EC50: 12.9nM
Assay Description:
Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assay
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Target
Free fatty acid receptor 4
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.31E+3nM
Assay Description:
Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assay
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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PubMed
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
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Affinity Data
EC50: 11nM
Assay Description:
Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50343141
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18.6nM
Assay Description:
Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilization
More data for this Ligand-Target Pair
Target Info
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