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Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM34152'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  2.20nMAssay Description:Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  2.20nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM34152(CHEMBL362628 | E-6801)
Affinity DataKi:  312nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed