Report error Found 8 Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM25756'
Affinity DataKd: 15nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Mouse)
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Displacement of [3H]CGP12177 from mouse beta1 adrenoceptor expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
Affinity DataKd: 55nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]CGP12177 from human beta1 adrenoceptor expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Tested for beta-1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o...More data for this Ligand-Target Pair
