Found 3 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM36485' TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 37.5nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
3D Structure (crystal)TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 367nMpH: 7.5 T: 2°CAssay Description:ATP-site competition binding assay using Mps1 Kinase inhibitors in LanthaScreen Eu time-resolved FRET (TR-FRET) technology from Invitrogen.More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of recombinant human GST-tagged Mps1/TTK (507 to 1400 residues) using recombinant cetn2 as substrate in presence of [gamma-32P]ATP measure...More data for this Ligand-Target Pair
