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Found 4 Enz. Inhib. hit(s) with Target = 'Group 10 secretory phospholipase A2' and Ligand = 'BDBM50458617'
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458617(CHEMBL4215835)
Affinity DataIC50:  14nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458617(CHEMBL4215835)
Affinity DataIC50:  14nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458617(CHEMBL4215835)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human sPLA2-10 using human HDL as substrate pretreated for 20 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458617(CHEMBL4215835)
Affinity DataIC50:  75nMAssay Description:Inhibition of mouse sPLA2-10More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed