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Found 4 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor antagonist protein' and Ligand = 'BDBM50331042'
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataKi:  11nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Arg-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed