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Found 2 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM23776'
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23776((2R)-2-amino-3-[(1,1-diphenylpentyl)sulfanyl]propa...)
Affinity DataKi:  175nM ΔG°:  -38.2kJ/molepH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23776((2R)-2-amino-3-[(1,1-diphenylpentyl)sulfanyl]propa...)
Affinity DataIC50:  319nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed