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Found 3 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM50572933'
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572933(CHEMBL4861379)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572933(CHEMBL4861379)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572933(CHEMBL4861379)
Affinity DataIC50:  230nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed