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Found 6 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50518026'
TargetMu-type opioid receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-Diprenorphine from mu opioid receptor (unknown origin) expressed in sf9 insect cell membranes after 1 hr by liquid scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataKi:  42nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataEC50:  180nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataEC50:  940nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataEC50:  940nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293T cells co-transfected with venus-tagged N-terminal beta-arrestin-2 assessed as incre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518026(CHEMBL4449152)
Affinity DataEC50:  180nMAssay Description:Agonist activity at Gi/o coupled human mu opioid receptor expressed in HEK293T cells co-expressing luciferase based cAMP biosensor and GRK2 assessed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed