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Found 3 Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50121180'
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121180(5'-(3-chlorophenyl)spiro[cyclohexane-1,3'-indol]-2...)
Affinity DataIC50:  56nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121180(5'-(3-chlorophenyl)spiro[cyclohexane-1,3'-indol]-2...)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121180(5'-(3-chlorophenyl)spiro[cyclohexane-1,3'-indol]-2...)
Affinity DataIC50:  477nMAssay Description:Inhibition of 3 nM [3H]-R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed