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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50569444'
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  160nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Mus musculus)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  340nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGI2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  7.37E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells by cell-free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed