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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase SIK2' and Ligand = 'BDBM192714'
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM192714(US11725011, Compound YKL-05-95 | YKL-05-095 (3))
Affinity DataIC50:  6nMAssay Description:IC50's for selected compounds in Table 5 below were measured by Caliper-based mobility shift assay (PerkinElmer). For these experiments, full len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM192714(US11725011, Compound YKL-05-95 | YKL-05-095 (3))
Affinity DataIC50:  6nMpH: 8.0Assay Description:IC50‘s for HG-9-91-01 derivatives were measured by Caliper-based mobility shift assay (PerkinElmer). For these experiments, full length His6-MBP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed