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Found 4 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50440284'
TargetToll-like receptor 8(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells by reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human TLR8 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.16E+4nMAssay Description:A stable HEK-Blue-hTLR8 cell line was purchased from InvivoGen (Cat. #: HEK-Blue-htlr8, San Diego, Calif., USA). These cells were designed for studyi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  7.87E+3nMAssay Description:The compounds were gradient diluted with DMSO in 3-fold using liquid work station POD starting at a concentration of 10 mmol/L and 10 points were dil...More data for this Ligand-Target Pair
In DepthDetails US Patent