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TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282744(CHEMBL4167504)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282745(CHEMBL4171153)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282746(CHEMBL4160945)
Affinity DataEC50: <10nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50085044(2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-phen...)
Affinity DataEC50:  1.40nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282748(CHEMBL4164063)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282746(CHEMBL4160945)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282749(CHEMBL4159869)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282750(CHEMBL4164343)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282751(CHEMBL4163242)
Affinity DataEC50:  50nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282748(CHEMBL4164063)
Affinity DataEC50:  30nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50150998(2-[(4-methoxyphenoxycarbonyl)({4-[2-(5-methyl-2-ph...)
Affinity DataEC50:  595nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282752(CHEMBL4174598)
Affinity DataEC50: <10nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282750(CHEMBL4164343)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282753(CHEMBL4162949)
Affinity DataEC50:  30nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  4nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282754(CHEMBL4174713)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282755(CHEMBL4160661)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282754(CHEMBL4174713)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282756(CHEMBL4159590)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282753(CHEMBL4162949)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282757(CHEMBL4170881)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282759(CHEMBL4160416)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282760(CHEMBL4174996)
Affinity DataEC50:  300nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282761(CHEMBL4167789)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282751(CHEMBL4163242)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282752(CHEMBL4174598)
Affinity DataEC50:  2.00E+3nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50085044(2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-phen...)
Affinity DataEC50:  122nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282749(CHEMBL4159869)
Affinity DataEC50:  80nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282761(CHEMBL4167789)
Affinity DataEC50: <10nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282760(CHEMBL4174996)
Affinity DataEC50:  20nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282759(CHEMBL4160416)
Affinity DataEC50:  200nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282757(CHEMBL4170881)
Affinity DataEC50: <10nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282744(CHEMBL4167504)
Affinity DataEC50:  200nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282756(CHEMBL4159590)
Affinity DataEC50:  20nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282755(CHEMBL4160661)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50150998(2-[(4-methoxyphenoxycarbonyl)({4-[2-(5-methyl-2-ph...)
Affinity DataEC50:  3nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50282745(CHEMBL4171153)
Affinity DataEC50:  10nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263659(N-[2-(3-(3-hydroxymethylphenyl)-7-methoxynaphth-1-...)
Affinity DataEC50:  0.760nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263602(N-[2-(3-phenyl-7-methoxynaphth-1-yl)ethyl] acetami...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263713(N-[2-(3-(3-Formylphenyl)-7-methoxynaphth-1-yl)ethy...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263661(N-[2-(3-(3-Hydroxymethylphenyl)-7-methoxynaphth-1-...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263662(N-[2-(3-(3-Hydroxymethylphenyl)-7-methoxynaphth-1-...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263716(N-[2-(3-(3-Bromomethylphenyl)-7-methoxynaphth-1-yl...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263758(N-[2-(3-(3-Aminophenyl)-7-methoxynaphth-1-yl)ethyl...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263551(N-[2-(3-(3-Methylaminophenyl)-7-methoxynaphth-1-yl...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263600(N-[2-(3-(3-Dimethylaminophenyl)-7-methoxynaphth-1-...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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