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TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194658((2R)-N-(1-cyclopropylmethyl-4-piperidinylmethyl)-1...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194659((2R)-N-(1-cyclopentylmethyl-4-piperidinylmethyl)-1...)
Affinity DataKi:  0.190nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194640((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluoroph...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M4(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194654((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194641((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluoroph...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194645((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluoroph...)
Affinity DataKi:  0.480nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM82372(CAS_22254-24-6 | Ipratropium | NSC_3746)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM82372(CAS_22254-24-6 | Ipratropium | NSC_3746)
Affinity DataKi:  0.510nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194655((2R)-N-(1-cyclopentyl-4-piperidinylmethyl)-1-((2S,...)
Affinity DataKi:  0.510nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194642((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluoroph...)
Affinity DataKi:  0.510nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194639((2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M5(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.540nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M4(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM82372(CAS_22254-24-6 | Ipratropium | NSC_3746)
Affinity DataKi:  0.660nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50109647(2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrro...)
Affinity DataKi:  0.840nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank


TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50109647(2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrro...)
Affinity DataKi:  0.840nMAssay Description:Binding affinity (Ki) against binding of [3H]NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095656(2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-met...)
Affinity DataKi:  0.880nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194657((2R)-N-(1-ethyl-4-piperidinylmethyl)-1-((2S,4R)-4-...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129387((R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hyd...)
Affinity DataKi:  0.980nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129390((R)-1-[4-(2-Amino-ethyl)-4-ethyl-piperidin-1-yl]-2...)
Affinity DataKi:  1nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50129399((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclope...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194649((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095679(2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hyd...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50129392((R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249758(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human NPYY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129392((R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50129387((R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hyd...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249833(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095662(2-Cyclopentyl-2-hydroxy-N-[1-(3-methyl-benzyl)-pip...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095657((R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129397((R)-1-[4-(2-Amino-ethyl)-4-methyl-piperidin-1-yl]-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095657((R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM82372(CAS_22254-24-6 | Ipratropium | NSC_3746)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194643((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM85787(Compound A)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50129410((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M5(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM82372(CAS_22254-24-6 | Ipratropium | NSC_3746)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129410((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50095656(2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-met...)
Affinity DataKi:  2nMAssay Description:Ability to inhibit binding of [3H]-NMS was determined by receptor binding assay using membranes from chinese hamster ovary (CHO) cells expressing clo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129399((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclope...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095680(2-Cyclopentyl-2-hydroxy-N-[1-(5-methyl-thiophen-3-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50129409((R)-1-(3-Aminomethyl-pyrrolidin-1-yl)-2-((R)-3,3-d...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50109650(CHEMBL369062 | N-{2-[(1-Cyclohexylmethyl-piperidin...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity (Ki) against binding of [3H]NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50095662(2-Cyclopentyl-2-hydroxy-N-[1-(3-methyl-benzyl)-pip...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M5(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50109647(2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrro...)
Affinity DataKi:  2.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank


TargetMuscarinic acetylcholine receptor M5(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50109647(2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrro...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity (Ki) against binding of [3H]NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetMuscarinic acetylcholine receptor M1(Human)
Banyu Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50095670(CHEMBL147653 | N-(1-Benzyl-piperidin-4-yl)-2-(3,3-...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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