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Found 10 with Last Name = 'silva' and Initial = 'tg'
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50320887(3-(2-Chloro-6-fluoro-benzyl)-5-(2,4-dichlorobenzyl...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50320886(3-(2-Bromo-benzyl)-5-(4-methanesulfonyl-benzyliden...)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50320884(3-(3-Chloro-benzyl)-5-(4-methanesulfonyl-benzylide...)
Affinity DataKi:  4.30E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50320885(5-Bipheny-4-ylmethylene-3-(3-chloro-benzyl)-thiazo...)
Affinity DataKi:  4.36E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469275(CHEMBL4290673)
Affinity DataIC50:  180nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469275(CHEMBL4290673)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469276(CHEMBL4282782)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469276(CHEMBL4282782)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  3.09E+3nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed