Compile Data Set for Download or QSAR
maximum 50k data
Found 32 of kd for UniProtKB: P34975
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021327(3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...)
Affinity DataKd:  625nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50497042(CHEMBL3249799)
Affinity DataKd:  1.00E+4nMAssay Description:Displacement of [3H]-(-)-naloxone from opiate receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021323(3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...)
Affinity DataKd:  137nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)
Affinity DataKd:  625nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50452273(Dihydromorphine)
Affinity DataKd:  830nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21130(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)
Affinity DataKd:  1nMAssay Description:Binding affinity to rat kappa opioid receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKd:  4.5nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021328(3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...)
Affinity DataKd:  0.300nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKd:  1nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021322(3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...)
Affinity DataKd:  179nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataKd:  0.0500nMAssay Description:Dissociation constant against D216N,D217N,E218Q EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataKd:  0.0290nMAssay Description:Dissociation constant against wild type EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataKd:  0.0380nMAssay Description:Dissociation constant against E203Q,D204N,D206N,E209Q EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataKd:  0.0500nMAssay Description:Dissociation constant against E203Q,D204N,D206N EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKd:  154nMAssay Description:Evaluated for Opioid receptor mu 1 affinity against the receptor site model site 1(mu1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021328(3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...)
Affinity DataKd:  4.16E+3nMAssay Description:Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50452273(Dihydromorphine)
Affinity DataKd:  200nMAssay Description:Compound was evaluated for opioid receptor affinity against the receptor site model site 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021327(3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...)
Affinity DataKd:  625nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021322(3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...)
Affinity DataKd:  2.63E+4nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021322(3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...)
Affinity DataKd:  2.63E+4nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021323(3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...)
Affinity DataKd:  3.70E+3nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021323(3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...)
Affinity DataKd:  3.70E+3nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021324(3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...)
Affinity DataKd:  83nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021324(3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...)
Affinity DataKd:  833nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021324(3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...)
Affinity DataKd:  833nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021322(3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...)
Affinity DataKd:  179nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021323(3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...)
Affinity DataKd:  137nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021327(3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...)
Affinity DataKd:  8.33E+3nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021327(3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...)
Affinity DataKd:  8.33E+3nMAssay Description:Opioid receptor affinity against the receptor site model site 5 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)
Affinity DataKd:  1.00E+4nMAssay Description:Compound was evaluated for opioid receptor affinity against the receptor site model site 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKd:  1nMAssay Description:Displacement of [3H]-(-)-naloxone from opiate receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021324(3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...)
Affinity DataKd:  83nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed