TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: <1nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: <1nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 2nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 2nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 4nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 4nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 4nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 5nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 6.60nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 6.80nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 7nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 7nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 7nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 7nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 7nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 8nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 9nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 14nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 15nMAssay Description:For the SARS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 16nMAssay Description:For the SARS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 17nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 17nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus 14)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Human rhinovirus serotype 14 3C protease preincubated for 1 hr followed by Cys(PT14M)-Ala-Ile-Phe-Gln'Gly-Pro-Asp-Phe(4-NH2)-OH substra...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 19nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 20nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 23nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 25nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 30nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 30nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 30nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 30nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 30nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 31nMAssay Description:For the SARS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 32nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre
Experimental Drug Development Centre
Affinity DataIC50: 32nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair