Compile Data Set for Download or QSAR
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Report error Found 11 of ec50 for UniProtKB: P25101
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045246(Ac-D-Dip-Orn-Asp-Ile-Ile-Trp | CHEMBL2370066)
Affinity DataEC50:  13nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045264(Ac-D-Dip-Leu-Asp-Val-Ile-Trp | CHEMBL315841)
Affinity DataEC50:  17nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045263(Ac-D-Dip-Glu-Asp-Ile-Ile-Trp | CHEMBL407269)
Affinity DataEC50:  25nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045224(Ac-D-Dip-Leu-Phe-Ile-Ile-Trp | CHEMBL387200)
Affinity DataEC50:  580nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045256(CHEMBL2370067 | D-Dip-Leu-Asp-Ile-Ile-Trp)
Affinity DataEC50:  1.90E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045234(Ac-D-Dip-Leu-Asp-Ile-Ile-Tyr | CHEMBL313344)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50499310(CHEMBL3736433)
Affinity DataEC50: <5.01E+3nMAssay Description:Agonist activity at human wild-type ETA receptor expressed in CHO-K1 cells assessed as calcium level by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Affinity DataEC50: <5.01E+3nMAssay Description:Agonist activity at human wild-type ETA receptor expressed in CHO-K1 cells assessed as calcium level by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50499311(CHEMBL3736156)
Affinity DataEC50: <5.01E+3nMAssay Description:Agonist activity at human wild-type ETA receptor expressed in CHO-K1 cells assessed as calcium level by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045249(Ac-D-Dip-Leu-Asp-Ile-Val-Trp | CHEMBL86703)
Affinity DataEC50:  6.00E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50516235(CHEMBL4563408)
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of [125I]endothelin-1 from recombinant human ETA receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed