Compile Data Set for Download or QSAR
maximum 50k data
Found 39 of ic50 for UniProtKB: Q64737
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016658(2-{4-[3-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)
Affinity DataIC50:  0.0180nMAssay Description:Inhibition of the GAR transformylase in L1210More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016660(2-{4-[2-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)
Affinity DataIC50: >0.0200nMAssay Description:Inhibition of the GAR transformylase in L1210More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022739((6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50:  10nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50306576((S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo...)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50281129((S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3...)
Affinity DataIC50:  65nMAssay Description:Tested for the inhibition against the human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50171511((S)-2-(4-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[...)
Affinity DataIC50:  150nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022739((6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50:  500nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022739((6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50:  500nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022741((5RS, 6RS) 2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4,5,6...)
Affinity DataIC50:  720nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50005518((S)-2-(4-(2-((R)-2-amino-4-oxo-1,4,5,6,7,8-hexahyd...)
Affinity DataIC50:  780nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50005518((S)-2-(4-(2-((R)-2-amino-4-oxo-1,4,5,6,7,8-hexahyd...)
Affinity DataIC50:  780nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM22590((2S)-2-[(4-{2-[(6R)-2-amino-4-oxo-1H,4H,5H,6H,7H,8...)
Affinity DataIC50:  780nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50272272(CHEMBL502528 | N-{4-[5-(2-Amino-4-oxo-4,7-dihydro-...)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50171513((S)-2-(4-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50272273(CHEMBL526928 | N-{4-[6-(2-Amino-4-oxo-4,7-dihydro-...)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50306577((S)-2-({5-[5-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249877((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...)
Affinity DataIC50:  5.51E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249876(CHEMBL490934 | N-{4-[3-(2-Amino-4-oxo-3,4-dihydrot...)
Affinity DataIC50:  8.52E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022741((5RS, 6RS) 2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4,5,6...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022740(2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4-dihydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249954(CHEMBL491298 | N-{4-[6-(2-Amino-4-oxo-3,4-dihydrot...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249953(CHEMBL491129 | N-{4-[5-(2-Amino-4-oxo-3,4-dihydrot...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50272231((S)-2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022740(2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4-dihydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249875(CHEMBL522455 | N-{4-[2-(2-Amino-4-oxo-3,4-dihydrot...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022740(2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4-dihydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016657(2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-pteridin-6-yl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of the GAR formyl transferase in L1210More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50003059(2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,9b-octahydro-2,...)
Affinity DataIC50: >4.00E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration of the compound inhibiting GAR transformylase enzyme of L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022741((5RS, 6RS) 2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4,5,6...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50003058(2-[4-(7-Amino-9-oxo-8,9-dihydro-2,5,6,8-tetraaza-c...)
Affinity DataIC50: >9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50003057(7-Amino-1,2,3-trimethyl-2,8-dihydro-2,5,6,8-tetraa...)
Affinity DataIC50: >9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50171511((S)-2-(4-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249877((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...)
Affinity DataIC50:  5.51E+6nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed