Compile Data Set for Download or QSAR
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TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240845(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKd:  0.160nMAssay Description:In vitro inhibition of [3H]-NT binding to human striatal Neurotensin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to human NTS1R assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50159216(CHEMBL3785364)
Affinity DataKd:  0.440nMAssay Description:Binding affinity to NTSR1 in human HT-29 cells after 2 hrs by liquid scintillation counting in presence of NTSR2 ligand (S)-2-((2S,3S)-2-(2-((S)-1-((...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50159216(CHEMBL3785364)
Affinity DataKd:  0.510nMAssay Description:Binding affinity to NTSR1 in human HT-29 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKd:  0.510nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50159216(CHEMBL3785364)
Affinity DataKd:  0.580nMAssay Description:Binding affinity to human NTSR1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKd:  0.590nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240845(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKd:  0.630nMAssay Description:Displacement of [3H]NT(8-13) from wild type human NTR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKd:  0.680nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50276350(((N-methyl-Arg)-Lys-Pro-(L-neo-Trp)-(tert-Leu)-Leu...)
Affinity DataKd:  1.55nMAssay Description:Binding affinity to human recombinant NTS1 in HEK293T cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509508(CHEMBL4534768)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 75 mins in presence of NT (8 to 13) followed by compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509510(CHEMBL4564746)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells preincubated for 20 mins to 2 hrs followed by addition of NT (8 to 13)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 75 mins in presence of NT (8 to 13) followed by compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells preincubated for 20 mins to 2 hrs followed by addition of NT (8 to 13)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50618615(CHEMBL1170627)
Affinity DataKd:  5.70nMAssay Description:Binding affinity to human NTS1R assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKd:  6.30nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 60 mins in presence of NT (8 to 13) without compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509513(CHEMBL4537266)
Affinity DataKd:  6.80nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 75 mins in presence of NT (8 to 13) followed by compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509510(CHEMBL4564746)
Affinity DataKd:  8.10nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 75 mins in presence of NT (8 to 13) followed by compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50248034(CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...)
Affinity DataKd:  8.90nMAssay Description:Displacement of [3H]SR48692 from wild type human NTR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509508(CHEMBL4534768)
Affinity DataKd:  10nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 60 mins in presence of NT (8 to 13) without compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509510(CHEMBL4564746)
Affinity DataKd:  15nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 60 mins in presence of NT (8 to 13) without compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50509513(CHEMBL4537266)
Affinity DataKd:  26nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 60 mins in presence of NT (8 to 13) without compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50241512(c(Lys-Lys-Pro-Tyr-Ile-Leu-Lys-Lys-Pro-Tyr-Ile-Leu)...)
Affinity DataKd:  150nMAssay Description:Binding affinity to human recombinant NTS1 in HEK293T cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed